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Q &A w/
Claudia
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A new feature we just added to Qwixo.com is a section called Q & A with Claudia. Each month our in-house reporter, Claudia Verela will be interviewing key individuals from around the country regarding important information that may affect you, and the ones close to you. 

subject: N1H1 virus
date: January, 2010

Our first Q & A topic is the “N1H1 virus”, and Claudia interviewed Dr. Paul Sicola, Emergency Medicine / Family Practice Physician, Med-Plus Urgent Care Clinics (MI).  

 
 
 
What is the official name of H1N1 and where did the term “swine flu” originate?
The new and official nomenclature of Influenza A is H1N1 and is the designation for the seasonal flu.

Swine influenza (also called Pig influenza, swine flu, hog flu and pig flu) is an infection by any one of several types of swine influenza virus. Swine influenza virus (SIV) or S-OIV (swine-origin influenza virus) is any strain of the influenza family of viruses that is endemic in pigs. As of 2009, the known SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H3N1, H3N2, and H2N3.

The current swine influenza A (H1N1) virus has been found to be a mix of human, pig (swine), and bird flu viruses, and since a lot of infected pigs haven't been found, it is not technically a swine flu. There are three main Influenza strains, A, B, and C. A is found in Humans and Pigs, C rarely in pigs, and B has not been reported in pigs.

Swine influenza was first proposed to be a disease related to human influenza during the 1918 flu pandemic, when pigs became sick at the same time as humans. The first identification of an influenza virus as a cause of disease in pigs occurred about ten years later, in 1930.
 

How was the H1N1 virus discovered?
Where this pig/ bird/ human flu super virus came from remains unknown. But what we do know is that a five-year-old boy, Edgar Hernandez, fell ill with what has now been diagnosed as the A (H1N1) virus, and is now thought to be the first known victim. The boy survived, but following his illness, around 800 people in his tiny town, La Gloria, southwest Mexico, also fell ill with a mysterious flu.
 

When was it detected first?
Swine influenza was first proposed to be a disease related to human influenza during the 1918 flu pandemic, when pigs became sick at the same time as humans. The first identification of an influenza virus as a cause of disease in pigs occurred about ten years later, in 1930.
 
 
How do symptoms compare to regular Influenza?
According to the Centers for Disease Control and Prevention (CDC), in humans the symptoms of the 2009 "swine flu" H1N1 virus are similar to those of influenza and of influenza-like illness in general. Symptoms include fever, cough, sore throat, body aches, headache, chills, and fatigue. The 2009 outbreak has shown an increased percentage of patients reporting diarrhea and vomiting. While only mild symptoms are experienced by the majority of people, some have more severe symptoms.

Those at risk of a more severe infection include: asthmatics, diabetics, those with obesity, heart disease, the immunocompromised, children with neurodevelopmental conditions, and pregnant women. In addition, even for persons previously very healthy, a small percentage of patients will develop viral pneumonia or acute respiratory distress syndrome. This manifests itself as increased breathing difficulty and typically occurs 3–6 days after initial onset of flu symptoms.

Similar to other influenza viruses, pandemic H1N1 is typically contracted by person to person transmission through respiratory droplets. Symptoms usually last 4–6 days. To avoid spreading the infection, it is recommended that those with symptoms stay home, away from school, work, and crowded places.

The 2009 H1N1 virus is not zoonotic swine flu, as it is not transmitted from pigs to humans, but from person to person.
 
 
Are there mutations of the strain?
Yes there are. All viruses have the ability to mutate into similar strains, and this one has many times over the years. Control of swine influenza by vaccination has become more difficult in recent decades, as the evolution of the virus has resulted in inconsistent responses to traditional vaccines. The challenge is to find vaccinations which will prevent transmission, with the objective being its complete eradication as w polio, etc. (Although these viruses still exist in the lab setting only).
 
 Where can it be found and where can we get it?
Well, it is pandemic, as mentioned earlier it can be found in animals but humans can only get H1N1 from other humans, however people who work with poultry and swine, especially people with intense exposures, are at increased risk.
 
 How can you tell if you have H1N1 or just the flu?
Confirmation is made only in the lab, and not clinically, which seems to be a developing trend, albeit non-confirmatory, leading to possible over-diagnosis.

It is very difficult to differentiate initially, with the above exceptions in symptomatology. The CDC (Center for Disease Control) recommends the RT-PCR test.

 
What are the ways to get it and how is it transmitted?
It is usually transmitted from person to person through direct physical contact; therefore vigilant personal hygiene is imperative in prevention of its transmission. Its origin in humans was from pigs, and certain avian species, but mainly transmitted person to person currently.

Spread of 2009 H1N1 virus is thought to occur in the same way that seasonal flu spreads. Flu viruses are spread mainly from person to person through coughing or sneezing by people with influenza. Sometimes people may become infected by touching something – such as a surface or object – with flu viruses on it and then touching their mouth or nose.

 
 How serious is it compared to similar past flu viruses?
The 2009 swine flu has been compared to other similar types of influenza virus in terms of mortality: In the US it appears that for every 1000 people who get infected, about 40 people need admission to hospital and about one person dies. There are fears that swine flu will become a major global pandemic at the end of the year. It also appears that it is bi-phasic with the latter phase coming in several months after its initial decline. With vaccination, we anticipate the morbidity will certainly be much less severe and less prevalent.

It is very difficult to differentiate initially, with the above exceptions in symptomatology. The CDC (Center for Disease Control) recommends the RT-PCR test.

 
 Is Tamiflu the only medicine that’s available to fight the virus? Who should get vaccinated?
No, there is one other medicine, Relenza ( zanamivir) which is also effective. Of concern is the fact that many of our conventional anti-virals are ineffective, H1N1 appears to have an “intelligence” that gives it the ability to mutate and develop this type of resistance against some of our most powerful anti-virals.

The suggested guidelines for those to be vaccinated are:

Parents/guardians of children younger than 6 months of age, People 6 months to 24 years of age, and People 25 to 64 years of age who are at higher risk for 2009 H1N1 flu complications because of an underlying health condition or compromised immune systems.
 
 What precautions should be taken?
This is a loaded question with a short and a long answer.

The Short Answer:

Take these everyday steps to protect your health:

Cover your nose and mouth with a tissue when you cough or sneeze. Throw the tissue in the trash after you use it. Wash your hands often with soap and water, especially after you cough or sneeze. Alcohol-based hand cleaners are also effective. Avoid touching your eyes, nose or mouth. Germs spread this way. Try to avoid close contact with sick people. Stay home if you are sick until at least 24 hours after you no longer have a fever (100°F or 37.8°C) or signs of a fever (without the use of a fever-reducing medicine, such as Tylenol). Read detailed information about how long to stay away from others. Follow public health advice regarding school closures, avoiding crowds and other social distancing measures.

If you must have close contact with a sick person (for example, hold a sick infant), try to wear a facemask or N95 disposable respirator.

The Long Answer:

Get Vaccinated. Vaccination is the best protection against contracting the flu. You need two vaccines to be fully protected this year. The seasonal flu vaccine is different from the H1N1 (Swine) flu vaccine. The CDC is encouraging people to get both vaccinations. Get both vaccinations as soon as possible.

Find a Flu Clinic near you and Get Vaccinated. Visit the Google Flu Shot Locator or our Flu Shot Locator page, to find flu shots in your area.

If you do contract the flu, talk to your doctor about antivirals. Antiviral drugs are prescription medicines (pills, liquid or an inhaler) that can be used for prevention or treatment of flu viruses. If you get sick, antiviral drugs can make your illness milder and make you feel better faster. Two types of antivirals, Oseltamivir (TAMIFLU) and Zanamivir (RELENZA) may be prescribed for the H1N1 flu. In addition, PERAMIVIR IV has been authorized under an Emergency Use Authorization (EUA) to treat certain patients with suspected or confirmed 2009 H1N1 flu virus infection.

Beware of fraudulent or bogus products. The FDA is alerting the public to be wary of Internet sites and other promotions for products that claim to diagnose, prevent, treat or cure the 2009 H1N1 flu virus. The FDA is advising offending Web sites to correct and/or remove promotions of fraudulent products or face enforcement action and the Federal Trade Commission has sent warning letters to Web site operators making questionable claims that their products can prevent, treat, or cure the H1N1 flu.

Keep things in perspective and maintain a hopeful outlook. It’s important to be cautious and get vaccinated, but try to limit your worry and agitation about the 2009 flu season. Bear in mind that vast majority of people who have contracted the H1N1 flu have recovered without requiring medical treatment.
 
 Who’s most susceptible, once contracted who does it pose most harm or threat to?
Immunocompromised patients; those who can’t fight infection due to 1) medication, i.e. chemotherapy in cancer patients, all patients with immune deficiencies, i.e., patients who can’t make antibodies to fight infection as in hepatitis, as well as the young and older population (not restricted to the elderly) and pregnancy.

Pregnancy weakens a woman’s immune system, so that she’s more likely to suffer pneumonia when she catches the flu. In earlier flu pandemics, infection also raised the risk of a premature birth.

So far, some 20 pregnant women have contracted the novel H1N1 virus now confirmed in more than 6,000 around the world. Three deaths have been confirmed in the United States. One of the three was a Texas woman who was pregnant. Her baby was delivered via Caesarean section while she was hospitalized.

Pregnant women with asthma and some other health conditions are particularly at risk for complications.

Risks from the virus are greater than the unknown risks to the fetus from the drugs Tamiflu and Relenza.

While 90 per cent of severe and fatal cases occur in people aged above 65 in seasonal flu, most of those who die from H1N1 flu are under the age of 50.
 
 What sort of treatment is the norm if the disease is contracted?
Tamiflu and Relenza within 48 hours preferably. Fluids to prevent dehydration, hand washing, acetaminophen for fever, ibuprofen for aches, and see your physician for prescription meds that can greatly ease the suffering until the course has run.
 
  How should you care for H1N1 at home (without a doctor visit)?
Rest, fluids, limit close contact, thorough hand washing, cough and sneeze on forearm sleeve, try a multivitamin.

I must emphasize, treating without a Physician’s exam, and proper testing is too risky and not recommended. Education is foremost as well to reduce transmission which may have otherwise occurred without proper counseling.

 
  The CDC estimated 4000 deaths discovered this year. 22,000 infected this year, is this accurate?
In my opinion, this is an underestimate along with the reported cases of the infected or sick… a large underestimate. I believe the numbers to be much higher.
 
  Its estimated the virus is active in 46 states, which have the highest reported cases?
According to Web MD, no state is immune, surely by now there are cases in every state. Reporting the incidence, on the other hand, is a different story.

Heavily populated states, per capita, i.e. New York, in New York City, are at much higher risk. One high school reported 1 in 3 confirmed student cases, resulting in a short closure. Michigan seems to be on the rise as well at an alarming rate. I feel it very unlikely that one day has gone by over the last month where I have not seen a patient infected with H1N1. The good news, the majority of cases are quite mild. Bacterial infectious disease has, in my opinion, caused an inordinate number of severe infections compared to previous years, most likely due to antibiotic over-prescribing resulting in the increasing resistance to conventional antibiotics. Resurgence of bacterial infections are much harder to treat, i.e., MRSA, (methicillin resistant staph aureus), TB, Legionella and even e.coli resistance which I attribute largely to antibiotic over prescription.)

 
 What are some of the Myth surrounding H1N1?
Some people believe that H1N1 is worse than seasonal flu. It isn’t. In the U.S., only one percent from all those infected with the virus die. This is around 300 people. There are thirty six thousand Americans who die annually because of the seasonal flu. Authorities were only worried because H1N1 has a strain which was never seen before.

Healthy people need not worry about getting the swine flu. This is wrong. It is just like seasonal flu because it can affect anyone. It only happens that those people with underlying health conditions are more prone to get the virus compared to healthy people.

Some people believe that the swine flu vaccine will only give them the flu. This is not possible because the virus found on the flu shot was killed already. Some people mistakes the common fever experienced as the flu itself. Fever experienced after the vaccine is actually the result of the body’s immune system fighting off a foreign substance. Also, some people think that the common cold they have is already the flu. What many people aren’t aware of is that flu season happens at the same time as cold season.

Some people believe that vaccines are harmful. The best way get immunity to the virus is by direct contact. This isn’t the right way to get immunity. This is in fact very dangerous. While you believe that you can get immunity when you are in direct contact with the virus itself, you are actually most likely to get the disease yourself rather than being healed.

People should stop eating pork since the virus is linked to that of the pigs’. This is absolutely wrong. The spread of the virus is only between humans. It comes from a sick person to a host’s mucous membranes such as the eyes, mouth and nose. There have been no proof yet that the virus is passed from a pig to a person.

These are some of the myths being tossed around regarding the swine flu virus. One good way to avoid this is through getting oneself educated. There are agencies such as the Centers for Disease Control and Prevention, World Health Organization, U.S. Food and Drug Administration and hospitals which are active in promoting information about the H1N1. In order to be better informed and protected, it is best that these health authorities are contacted.
 
   
 
 
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**The information and opinions in the above is provided for entertainment purposes only. We make no representations or warranties of any kind with respect to the accuracy or completeness of any information or content provided. The foregoing is not medical advice and you should not rely on it as such.

 
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